There are 8 Vatican Mysteries to solve! Some of them do require progress through the main quest or fieldworks, which will be mentioned in each solution below!
00:00 The Bulls of Blood Vatican Mystery Solution Guide
01:50 A Date To Remember Vatican Mystery Solution Guide
03:43 Secret of Secrets Vatican Mystery Solution Guide
04:58 House of God Vatican Mystery Solution Guide
06:33 Father And Son Vatican Mystery Solution Guide
08:29 Signs of Trouble Vatican Mystery Solution Guide
10:06 A Snake in the Garden Vatican Mystery Solution Guide
11:34 A Free Spirit Vatican Mystery Solution Guide
The
Bulls of Blood Vatican mystery can be found in the Saint Angelo Castle section of the Vatican. Through the courtyard of Angels we can find a note in a side room that starts the mystery then progress through the rooms to find two pictures of bulls. We need to interact with them to rotate the pictures so that the brown bull is on top. This opens a series of secret doors, giving us a shortcut to the exit of the castle.
The
A Date to Remember Vatican mystery can be found in the Vatican museum. If you already have the blackshirt disguise it is recommended for getting through this restricted area to the enemy tent. Inside is a couple of notes we can grab and a chest that is locked with a code. The code to open it and solve the mystery is
6380. Inside we can find the Vatican Medicine Exploration Book.
The
Secret of Secrets Vatican mystery can be found in the office of the Sistine Chapel. Inside is a couple notes, including one in the desk drawer, as well as a safe that is locked with a code. The code to open it and solve the mystery is
4471.
The
House of God Vatican mystery can be found on the balcony before the Borgia Tower. This area can be reached by climbing the scaffolding behind the stage in the main courtyard. There will be a guard up here, so take him out if he gives us any trouble. At the top will be a self contained puzzle that we need to solve using the lever to open secret compartments and gain components to place. Once completed, we will be rewarded with the Vatican Relics Exploration Book.
The
Father and Son Vatican mystery can be found in the Borgia Tower, after completing the A Nun in Trouble fieldwork. Through that fieldwork we gain the key to open the locked doors in this tower. So climb up the scaffolding and go through the locked doors to find some notes and a chest locked with a code. The code to open it and solve the mystery is
5873.
The
Signs of Trouble Vatican mystery can be found on the altar in the Sistine Chapel after completing the A Nun in Trouble fieldwork. From grabbing the letter we will head to the excavation site to open a locked safe with the code
1891. Then return to the Sistine Chapel with the safe’s contents to complete this mystery.
The
A Snake in the Garden Vatican mystery can be started in an office on the top floor of the apostolic palace. The office door is locked, so we will need to climb out a nearby window and jump across the scaffolding to make it inside. There will be a letter on the desk that starts the mystery, then we just need to interact with the four books in the bookcase in the correct order to solve it. This order is
Crown, Triangle, Circle, Vortex, or from left to right
2, 4, 1, 3.
The
A Free Spirit Vatican Mystery can be found on the corkboard across from the tower of Nicholas entrance. Interact with the flyer here to begin the mystery. Then head down the road and up on to the roofs to find the black cat that is missing. Once we take a picture of it, we can return to the flyer to complete the mystery.